Commonly recommended for:

a) Prevention of chloroquine resistant malaria
b) Treatment of Brucella, Q fever, Lyme disease, Tularemia, Rickettsial disease


a) Prevention of malaria: 100mg tablet, 1 tablet by mouth, once a day, starting 2 days prior to, during and for 4 weeks after return from malaria endemic region.
b) Treatment of other illnesses: 100mg tablet, 1 tablet by mouth, twice a day for anywhere from 14 – 21 days depending on the illness (please consult a physician)

Take with food:


Pregnancy risk:

Avoid if pregnant

Alcohol drinking:


Breast feeding risk:

Avoid if breast feeding


Allergy to doxycycline or tetracycline or any part of the formulation
Children less than 8 years of age
Severe liver dysfunction

Special Precautions:

Can result in sun burn if skin is exposed; wear long sleeve clothing and protective hats during day light hours.

Common side effects:

Abdominal pain, nausea, vomiting,
Sunburn, rash, darkening of skin pigmentation
Rarely: increased intracranial pressure with headaches, liver toxicity, esophageal ulcers

Common drug interactions:

Increases levels of Coumadin (warfarin) resulting in increased bleeding time.
Increases levels of methotrexate.

Discuss above and other medication interactions with your pharmacist.

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